Plasmosorption is one of the modern methods of extracorporeal hemocorrection, which is based on the process of absorption of pathogenic components from the patient’s blood plasma on the surface of a special sorbent.
For this procedure, special equipment is used, with the help of which, at the first stage, whole blood is pre-divided into cellular elements and plasma.
Further, after passing through the sorption column, the plasma in contact with the sorbent leaves on its surface or in the thickness of the sorbent, substances that cause diseases (atherogenic lipoprotein fractions, circulating immune complexes, pathogenic immunoglobulins). The purified plasma is returned to the patient.
The following types of sorbents are used during this type of procedure:
Indications for plasmosorption are:
The main contraindications are:
The methodology of the plasmosorption procedure.
Before conducting a course of extracorporeal hemocorrection, the patient must undergo a number of general clinical studies, general and biochemical blood tests, and evaluate the parameters of the blood clotting system.
The calculation of the required volumes of the treated plasma is performed based on the data of the hematocrit, height, weight, and surface area of the patient’s body.
During the procedure, hemodynamics, electrocardiogram, blood oxygen saturation, and the patient’s pulse are constantly monitored.
To ensure the necessary speed of blood flow, during this procedure, the patient is punctured with several peripheral veins, or the central vein is catheterized.
Also, during plasmosorption, the following drugs are administered:
The duration of the procedure is several hours and depends not only on the target parameters for the treated plasma, but also on the speed of blood flow in the extracorporeal circuit.